Keith Appling scored 16 points and No. 7 Michigan State outlasted No. 15 Iowa 71-69 in overtime Tuesday night, handing the Hawkeyes their first home loss of the season.
Matt Costello had 11 points and 12 rebounds for the Spartans (19-2, 8-1 Big Ten), who avoided consecutive defeats despite missing injured starters Adreian Payne and Branden Dawson.
Costello's tip-in with 1:14 left gave Michigan State a 67-64 lead, and Russell Byrd's 3 with 34 seconds put Michigan State up by six.
Iowa still had a chance to force a second overtime, but Mike Gesell missed a driving layup at the buzzer.
Devyn Marble had 21 points for Iowa (16-5, 5-3), which went without a field goal for the final 10 minutes of regulation and until the final seconds of the 5-minute overtime.
The Hawkeyes boast one of the nation's deepest benches, and they kept threatening to run away from the undermanned Spartans early in the second half.
Michigan State wouldn't let it happen.
The tough-minded Spartans had an answer for nearly every basket that could have swung the momentum back in Iowa's favor.
Denzel Valentine finished with 12 points, including a crucial quick layup when the Hawkeyes seemed set for a transition basket. Travis Trice then followed with 3 to give Michigan State a 51-50 lead.
Iowa later went ahead by six points, but Appling — with his right shooting wrist heavily taped — hit a 3, and a layup and dunk by Costello made it 58-57 Spartans with 4:06 left.
The Hawkeyes had a chance to win in regulation, but Marble missed a runner just before the buzzer.
That was a theme that doomed the Hawkeyes, who didn't hit a field goal from the 9:56 mark of the second half until Marble's layup with 6 seconds left in OT.
Aaron White had 10 points for the Hawkeyes, who lost despite hitting 19 more free throws than Michigan State.
It was a tough loss for Iowa considering that it had been nearly a decade since Iowa City had seen a game this big.
Iowa hadn't hosted a Top 25 opponent as a ranked team since 2006, when it last went to the NCAA tournament. Even Iowa Gov. Terry Branstad made the 2-hour drive from Des Moines to see the program's biggest home game in years.
No. 4 Wichita State 57, Loyola (Ill.) 45: Cleanthony Early scored 23 points, including 12 of the 21 the Shockers scored in the second half, to help Wichita State remain unbeaten.
The Shockers (22-0, 9-0 Missouri Valley Conference) saw a 22-point second-half lead trimmed to nine in the game's final minutes but hung on to extend school records for winning streak and start to a season. The Shockers shot 23 percent (6 of 26) in the second half.
Freshman Milton Doyle scored 14 of his 16 points in the second half for the Ramblers (8-13, 3-6).
Virginia 68, Notre Dame 53. Malcolm Brogdon had 16 points, seven rebounds and six assists and the Cavaliers won their fourth straight, forcing the Fighting Irish into a season-high 20 turnovers.
The Irish (11-10, 2-6) have lost six of their last seven and their fourth home game, their most home losses since losing five during the 2005-06 season.
Cleveland St 82, E Illinois 68: Bryn Forbes scored 25 points and the Vikings defeated the Panthers, notching the 150th win for coach Gary Waters and making him the winningest coach in CSU program history.
Dylan Chatman led the Panthers with 19, Sherman Blanford scored 16, and Olivier 11.