NFL owners will vote on the sites of the 50th and 51st Super Bowls on Tuesday at their spring meetings.
The San Francisco area, where a new stadium is being built in Santa Clara, and South Florida are competing for the the 50th edition, to be held in February 2016. The loser in that bidding will go against Houston to host the 51st game the following year.
A three-quarters majority of the 32 owners is required on the first ballot. If neither city gets that, then a simple majority wins on the next ballot.
The 49ers' new home is scheduled to open for the 2014 season. The area hosted its only Super Bowl at Stanford Stadium in 1985.
Miami has staged 10, most recently in 2010. Only New Orleans has had as many Super Bowls.
Houston was host in 2004.